Coronary Artery Calcification.
نویسندگان
چکیده
Coronary artery calcification (CAC) is an established marker of subclinical atherosclerosis and an independent predictor of future coronary heart disease in the asymptomatic primary prevention population, particularly in the intermediate risk cohort. CAC also helps in reclassifying those patients and their risk of cardiovascular events into higher or lower risk categories. MESA (Multi-Ethnic Study of Atherosclerosis) is a National Heart, Lung, and Blood Institute-sponsored population-based medical research study involving 6,814 men and women from 6 U.S. communities without a medical history of clinical cardiovascular disease. The evidence from this population cohort revealed that CAC scoring was independently predictive and highly effective at risk stratification of major adverse cardiac events. This review provides available data based on MESA. We focus on the utility of CAC for cardiovascular disease risk stratification of individuals, and we describe its diagnostic value in identifying patients at risk.
منابع مشابه
Association between Coronary Artery Sclerosis and Dental Pulp Calcification in Patients Attending Sari Touba Clinic, 2019
Background and purpose: Coronary artery disease is a major cause of mortality, morbidity, and disability in society and patients incur high expenditure on treatment. Pulp stones are ectopic calcifications of the pulp vessel walls, so, they can have similar pathogenesis as those of other organs and coronary atherosclerosis. The purpose of this study was to investigate the correlation between cor...
متن کاملمطالعه غلظت سرمی و پلی مورفیسم rs1800799 پروموتور ژن MGP در بیماران با تنگی عروق کرونر
Background and purpose: Coronary artery stenosis is a progressive process associated with artery calcification. Although the role of matrix Gla protein (MGP) is not completely clear but its expression in vascular smooth muscle cells (VSMCs) and sub-endothelial macrophages suggests a role in vascular calcification. The rs1800799 is one of the polymorphisms oriented within transcription factor el...
متن کاملCoronary artery calcium (CAC) score – a prognostic tool in coronary artery disease?
Introduction: The aim of this study was to evaluate the impact of measurement of coronary artery calcification score (CAC) in patients with suspected coronary artery disease (CAD) and a normal myocardial perfusion scan. Methods: In a prospective study we measured the calcium score of 74 patients (29 m, 45 f, mean age 58.7 (m) and 64.4 (f)) with suspicion of CAD and a normal perfusion scan. In ...
متن کاملFast Computed Tomography Detection of Coronary Calcification in the Diagnosis of Coronary Artery Disease
Background The predominant cause of coronary artery calcification is atherosclerosis. Although fast x-ray computed tomography (CT) has been demonstrated to be a sensitive technique to detect coronary calcification, the increasing prevalence of calcification with age has been associated with a low specificity for identifying obstructive atherosclerosis. We hypothesized that the specificity of th...
متن کاملIncidence and significance of coronary artery calcification.
The incidence of coronary artery calcification was studied in 65 hearts obtained at necropsy. In cases over the age of 40 there was an incidence of coronary calcification of 79 per cent. The incidence increases with age and is slightly more common in men. These lesions occur more commonly in the left coronary circulation than the right. There is a strong association with aortic valve calcificat...
متن کاملCurrent understanding of coronary artery calcification
Coronary artery calcification (CAC) is highly prevalent in patients with coronary heart disease (CHD) and is associated with major adverse cardiovascular events. There are two recognized type of CAC-intimal and medial calcification, and each of them have specific risk factors. Several theories about the mechanism of vascular calcification have been put forward, and we currently believe that vas...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Global heart
دوره 11 3 شماره
صفحات -
تاریخ انتشار 2016